See how to determine the maximum range of a top loading balance, and learn how to calibrate it using a set of standard weights. Then we'll determine the deviation and percent difference in the actual weight…
Denaturation is a process that causes a protein to unfold and lose its shape, and it usually happens as a result of external stress. It’s an important concept for us to understand because we work with so many protein-…
In biomanufacturing, we use moist heat - saturated, pressurized steam - to kill microbes. But steam’s unique physical properties present some real challenges.
When steam cools, it condenses into water. The…
Learn how to make a simple type of media called LB+ which is commonly used for growing E. coli. In this demonstration, we'll also test the impact of pharmaceutical formulation - the process of how chemicals and…
Buffers are solutions that are able to resist changes in pH. In this experiment, we make a buffer of equal parts acetic acid and sodium acetate, and we observe what happens when we add drops of hydrochloric acid and…
Plate and frame filtration is widely used in food, beverage, pharma and chemical manufacturing. Let’s examine mixing, solubility, and tangential flow filtration of a suspension using the Buon Vino MiniJet Wine Filter…
Chromatography is a common technique to purify a pharma product. It’s how we break down a complex mixture into a single material. In this demonstration, we’ll use a mini chromatography column, the Sep-Pak C-18, to…
Environmental monitoring and microbiological testing play critical roles in ensuring the safety of patents and the efficacy of drugs and biologics by preventing their contamination with microbes. In this experiment, we’…
Transferring sterile liquids or cultures from one container to another is one of the most common tasks you'll perform in biomanufacturing. It's a skill that requires mental focus and attention to detail in order to…
The autoclave and sterile filtration are two common techniques we use to sterilize liquids and protect patients. In this demo, we’ll make some culture media and split it into three fractions. Then we’ll compare an…
