Upstream

Upstream processing is the earliest stage in biomanufacturing.

Upstream

Upstream processing is the earliest stage in biomanufacturing that involves propagating mammalian, yeast, insect or microbial cells for producing desired products such as antibiotics, amino acids, therapeutic proteins, vaccines and viral vectors for gene therapy. In order for upstream processing to occur, appropriate nutrients must be available and stable growth environments must be tightly regulated to support the growth of these cells. Slight changes in cell cultivation environments can result in toxic accumulations that can negatively impact the viability, quality and yield of the final product. In our Upstream Processing courses, students will learn key nutritional and growth conditions via hands-on experience in media preparation and through the operation of microbial fermenters and mammalian cell culture systems. 

Online Courses

BioNetwork has several online courses.

Training Solutions
View All Courses: Upstream
Advanced Biomanufacturing Training Program
This hybrid course offers 2 separate certifications. Students who complete all sections of this... more
Fundamentals of Biomolecules
Biomolecules are often the end product and a critical component of the bioprocessing and... more
Micropipetting Techniques for Precision & Accuracy
Micropipettes are common laboratory devices used to accurately dispense small volumes of liquid... more
Biopharmaceutical fermentation involves propagating mammalian, yeast, or microbial cells to produce... more
Micropipetting Techniques for Precision & Accuracy
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Centrifugation
eLearning
This module includes, the basics of centrifugation, effects of gravity on particles in suspension,... more
Chromatography
eLearning
In this interactive exercise, we'll explore the basic concepts of Chromatography. Then, you will ... more
Current Good Manufacturing Practices (CGMP)
eLearning
Current Good Manufacturing Practices, or CGMPs, help ensure the quality, safety, and efficacy of a... more
Deliberate Documentation
eLearning
Documentation is a critical part of any manufacturing process. Every manufacturing step is... more