Upstream

Upstream processing is the earliest stage in biomanufacturing.

Upstream

Upstream processing is the earliest stage in biomanufacturing that involves propagating mammalian, yeast, insect or microbial cells for producing desired products such as antibiotics, amino acids, therapeutic proteins, vaccines and viral vectors for gene therapy. In order for upstream processing to occur, appropriate nutrients must be available and stable growth environments must be tightly regulated to support the growth of these cells. Slight changes in cell cultivation environments can result in toxic accumulations that can negatively impact the viability, quality and yield of the final product. In our Upstream Processing courses, students will learn key nutritional and growth conditions via hands-on experience in media preparation and through the operation of microbial fermenters and mammalian cell culture systems. 

Online Courses

BioNetwork has several online courses.

Training Solutions
View All Courses: Upstream
Micropipetting Techniques for Precision & Accuracy
Micropipettes are common laboratory devices used to accurately dispense small volumes of liquid... more
Biopharmaceutical fermentation involves propagating mammalian, yeast, or microbial cells to produce... more
Fundamentals of Biomolecules
Biomolecules are often the end product and a critical component of the bioprocessing and... more
BioCertification Boot Camp
All students who complete the BioWork Certificate Program successfully are eligible to take the... more

Contact Us

Capstone Center
850 Oval Drive
Raleigh, NC 27695
Phone: 919-515-0232
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Autoclave Operation
eLearning
In this interactive lesson, we'll cover an overview of the autoclave, review safety considerations... more
Batch Documents
eLearning
In this interactive exercise, you will learn the importance of batch documents by reviewing the... more
Bioprocessing Part 1: Fermentation
Video
This video describes the role of the fermentation process in the creation of biological products... more
BioWork 3050: Measuring Weight
Video
See how to determine the maximum range of a top loading balance, and learn how to calibrate it... more
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