Upstream

Upstream processing is the earliest stage in biomanufacturing.

Upstream

Upstream processing is the earliest stage in biomanufacturing that involves propagating mammalian, yeast, insect or microbial cells for producing desired products such as antibiotics, amino acids, therapeutic proteins, vaccines and viral vectors for gene therapy. In order for upstream processing to occur, appropriate nutrients must be available and stable growth environments must be tightly regulated to support the growth of these cells. Slight changes in cell cultivation environments can result in toxic accumulations that can negatively impact the viability, quality and yield of the final product. In our Upstream Processing courses, students will learn key nutritional and growth conditions via hands-on experience in media preparation and through the operation of microbial fermenters and mammalian cell culture systems. 

Online Courses

Training Solutions
View All Courses: Upstream
Operations in Biotechnology Processes: An Overview
This course will focus on the details of the typical processing procedures utilized to produce a... more
Fundamentals of Biomolecules
Biomolecules are often the end product and a critical component of the bioprocessing and... more
Micropipetting Techniques for Precision & Accuracy
Micropipettes are common laboratory devices used to accurately dispense small volumes of liquid... more
Biopharmaceutical fermentation involves propagating mammalian, yeast, or microbial cells to produce... more

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Capstone Center
850 Oval Drive
Raleigh, NC 27695
Phone: 919-515-0232
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