Freeze-Drying Fundamentals
Learn the principles and techniques of manufacturing lyophilized biopharmaceutical products. Biologics, vaccines, and other pharmaceutical ingredients may require freeze-drying and moisture analysis for product stabilization and long-term storage. This course gives you a theoretical foundation and practical experience in lyophilization.
Topics Include
The course is 20 hours, conducted in two 8-hour sessions and one 4-hour session on the third day and covers:
- Principles of lyophilization: primary drying, secondary drying, eutectic points, and collapse temperatures
- Lyophilization cycle set up and operation
- Thermal analysis of product formulations using Differential Scanning Calorimetry (DSC) and Freeze-Drying Microscopy
- Residual moisture content analysis of finished product
- Troubleshooting lyophilization failures
Learning Objectives
- Discuss the principles and theory underlying lyophilization
- Perform freeze-dryer cycle development
- Relate product formulations to freeze-drying success
- Troubleshoot freeze-dried product failures
Audience
Technicians in pharmaceutical manufacturing including:
- Lyophilization specialists
- Validation Engineers
- Process Technicians
- Production Technicians
- Quality Control/Quality Assurance personnel
850 Oval DriveRaleigh, NC 27695
Instructor
Rebel Umphlett
Class Dates
- March 12, 2019
- March 13, 2019
- March 14, 2019
Class Days & Times
- Tue - 8:00 AM to 5:00 PM
- Wed - 8:00 AM to 5:00 PM
- Thu - 8:00 AM to 12:00 PM
Class Level
Intermediate
Intermediate
Lecture Hours
10.00
10.00
Lab Hours
10.00
10.00
Total Contact Hours
20.00
20.00
Building
BTEC
BTEC
Room
124
124
Format
Face-to-Face
Face-to-Face
Course ID
205228
205228